Know More about PVP VA64 VP/VA Copolymer
2024-11-25
PVP VA64 (INCI Name:VP/VA Copolymer) is a polymer material obtained by copolymerizing polyvinylpyrrolidone (PVP) with vinylpyrrolidone. PVP VA64 is widely used across various industries, particularly in cosmetics, pharmaceuticals, food products, and industrial applications.
Key Features:
• Good Solubility: PVP VA64 is a water-soluble polymer that forms a transparent solution in water, making it commonly used in the cosmetics and pharmaceutical industries.
• Adhesive Properties: It has excellent adhesion and film-forming properties, commonly used in coatings, adhesives, oral care products, hair sprays, and more.
• Stability: PVP VA64 exhibits good chemical stability, capable of withstanding certain temperature and humidity variations.
• Biocompatibility: In the pharmaceutical field, PVP VA64 is often used in drug formulations due to its excellent biocompatibility and safety.
Applications:
• Cosmetics: Frequently used in hair sprays, conditioners, mascaras, etc., as a film-forming agent and adhesive.
• Pharmaceuticals: Used as an excipient to aid in the dissolution and absorption of drugs.
• Food: Employed as a thickening agent, emulsifier, and more in the food industry.
• Industrial Applications: Used in textile coatings, adhesives, and other industrial products.
Main Functions:
• Provides excellent adhesion and film-forming effects.
• Enhances product stability and transparency.
• Improves the sensory properties of drugs or cosmetics (such as touch, spreadability, etc.).
Difference between PVP VA64, PVP K90, and PVP K30
PVP VA64, PVP K90, and PVP K30 are different derivatives of polyvinylpyrrolidone (PVP), primarily distinguished by their molecular weight, structure, and properties, making them suitable for various industries and applications. The main differences between them lie in their molecular weight, solubility, viscosity, and uses.
Below is a detailed comparison:
• Molecular Weight: Medium (lower than PVP K90 but higher than PVP K30).
• Structure: PVP VA64 is a copolymer of PVP and vinylpyrrolidone (VA), containing vinyl groups.
Features：
• Good water solubility and transparency, able to form transparent films.
• Faster dissolution rate compared to PVP K90, suitable for formulations requiring quick dissolution.
• Exhibits stronger adhesion and film-forming properties due to the presence of vinyl groups, making it ideal for applications with higher film requirements.
Main Uses
• Cosmetics: Used as a film-forming agent and thickener, commonly found in skincare products, hairspray, mascara, etc.
• Pharmaceuticals: Used as a solubility enhancer for drugs.
• Food: Used as an emulsifier and stabilizer in food products.
• Molecular Weight: High (higher than both PVP VA64 and PVP K30).
• Structure: Pure PVP, without vinyl groups.
Features
• High molecular weight, resulting in greater viscosity, and the films formed are strong and stable.
• Slower dissolution rate, typically requiring higher temperature and stirring.
• Provides strong adhesion and film strength, suitable for formulations that need enhanced structural integrity.
Main Uses
• Pharmaceuticals: Used as a binder and controlled-release agent in tablets and capsules.
• Cosmetics: Used to increase durability and adhesion, commonly found in hairsprays, mascaras, etc.
• Coatings: Used in applications requiring high viscosity and film strength.
• Molecular Weight: Medium (lower than PVP K90 but higher than PVP VA64).
• Structure: Pure PVP, similar to PVP K90 but with a lower molecular weight.
Features
• Medium viscosity with good water solubility.
• Easier to dissolve than PVP K90, but with lower viscosity and weaker film strength.
• Typically used in applications that do not require extremely high viscosity.
Main Uses
• Cosmetics: Used as a thickener, film-forming agent, and adhesive in products like face creams, shampoos, conditioners, etc.
• Pharmaceuticals: Used as a binder in tablets where lower adhesive strength is required.
• Food: Used for thickening and emulsifying in food products.
| Features/ Type | PVP VA64 | PVP K90 | PVP K30 |
| Molecular Weight | Medium (lower than K90, slightly higher than K30) | High (highest viscosity and film strength) | Medium (lower than K90, higher than VA64) |
| Solubility | Good, dissolves quickly | Dissolves slowly, requires higher temperature and stirring | Good, dissolves relatively quickly |
| Viscosity | Medium, moderate | High, provides strong adhesion and film strength | Medium, viscosity lower than PVP K90 |
| Film Strength | Moderate, relatively soft | High, good film strength and stability | Lower, film strength not as high as K90 |
| Transparency | Fairly good, suitable for applications requiring transparency | Good, suitable for applications requiring opaque films | Average, transparency is relatively poor |
| Main Applications | Cosmetics, food, pharmaceuticals (solubility enhancement) | Cosmetics (long-lasting), pharmaceuticals (controlled release, binding) | Cosmetics, pharmaceuticals (low adhesion strength requirements) |
Summary:
• PVP VA64 is suitable for formulations that require fast dissolution and good transparency, with a certain degree of adhesion. It is commonly used in cosmetics and food products.
• PVP K90, due to its high molecular weight and viscosity, is ideal for applications requiring high adhesive strength and strong film-forming properties. It is primarily used in the pharmaceutical industry and some high-performance cosmetics.
• PVP K30 has a molecular weight and viscosity between PVP VA64 and PVP K90, making it suitable for applications with moderate requirements for film strength and viscosity.
Benefits of Using PVP VA64 and PVP K30 Together
• Enhanced Adhesion and Film Formation:
PVP VA64 excels in forming transparent, soft, and elastic films, while PVP K30, with its higher molecular weight, improves adhesion and enhances the strength of the film. When used together, they can maintain flexibility while improving the durability of the film.
• Improved Rheological Properties:
PVP K30 is excellent at increasing viscosity, which enhances the rheology of the solution. On the other hand, PVP VA64 performs better in maintaining good solubility at lower concentrations. The combination of both helps adjust the flow properties and stability of the formulation.
• Optimized Solubility and Stability:
PVP VA64 has better solubility in water and is commonly used in formulations that require transparent solutions, whereas PVP K30 generally performs better at higher concentrations in terms of viscosity and solubility. Using both ensures that the product performs optimally across different concentration ranges.
Applications
• Cosmetic Industry:
The combination of PVP VA64 and PVP K30 can optimize the performance of products like hair sprays, mascaras, and skincare products. PVP VA64 provides good film formation and smoothness, while PVP K30 enhances the stability and longevity of the product.
• Pharmaceutical Industry:
PVP K30 can be used in drug capsule shells or as a binder for tablets, while PVP VA64 assists in the solubility and absorption of the drug. The combined use helps balance adhesion and solubility in drug formulations.
• Food Industry:
In food additives, PVP K30 provides higher viscosity and stability, while PVP VA64 offers better transparency and a lighter feel, making it suitable for emulsification, thickening, and similar applications.
Dosage and Considerations
• The ratio of PVP VA64 to PVP K30 is typically adjusted based on the needs of the formulation. Generally, PVP K30 concentration can be slightly higher due to its stronger adhesion and film strength properties. The concentration of PVP VA64 can be adjusted to achieve the desired transparency and flexibility.
• In aqueous systems, both PVPs typically work well together, but it is important to pay attention to the order of dissolution. It is usually recommended to dissolve PVP VA64 first, followed by the addition of PVP K30, to avoid any dissolution issues.
Benefits of Using PVP VA64 and PVP K90 Together
• Enhanced Film Strength and Flexibility
• PVP K90, with its higher molecular weight, provides a strong film structure and excellent adhesion, while PVP VA64 contributes flexibility and better water solubility. The combination ensures that the film maintains strength while remaining flexible and extensible.
• Optimized Solubility and Viscosity
• PVP VA64 demonstrates good solubility at lower concentrations, making it suitable for low-concentration formulations, while PVP K90 offers higher viscosity and stability. When used together, they optimize the rheological properties of the entire formulation, ensuring good performance in various applications.
• Enhanced Formulation Stability
• The high molecular weight of PVP K90 improves the stability of the solution, while PVP VA64, as a lower molecular weight component, enhances solubility and transparency. The combination prevents formulation issues caused by excessive viscosity, making it ideal for products that require high stability.
Wide Application Range
• Pharmaceuticals:
In pharmaceuticals, PVP K90 is used as a binder for tablets or a controlled-release agent, while PVP VA64 can enhance the drug's solubility. The combination of both ensures that both adhesion and solubility are addressed in complex drug formulations.
• Cosmetics:
In skincare, hair sprays, mascaras, and other cosmetic products, PVP K90’s high viscosity and longevity help maintain product performance, while PVP VA64 provides improved flexibility and comfort, enhancing the user experience.
• Food Additives:
In the food industry, PVP K90’s high adhesion is suitable for applications requiring enhanced product structure, while PVP VA64 offers transparency and smoothness at lower concentrations, making it ideal for emulsification and thickening purposes.
Applications
• Cosmetic Industry:
In cosmetics, the combination of PVP VA64 and PVP K90 can achieve different effects. For example, PVP K90 can be used to enhance adhesion and longevity, making it ideal for products like hair sprays and skincare, while PVP VA64 improves product softness and ease of application, enhancing the product's feel.
• Pharmaceutical Industry:
In drug formulations, PVP K90 is commonly used as a binder for tablets, improving the drug's cohesiveness and stability, while PVP VA64 is suitable for improving solubility, especially in drugs requiring controlled release or enhanced bioavailability.
• Food Industry:
In food formulations, PVP VA64 can serve as an emulsifier and stabilizer, while PVP K90 provides higher viscosity and structural support. Together, they can improve the texture and stability of food products.
Dosage and Considerations
• When using both, the ratio of PVP VA64 to PVP K90 should be adjusted according to the specific formulation needs. PVP VA64 concentration may be slightly higher, especially when transparency and good solubility are required, while PVP K90 concentration may be lower to prevent excessive viscosity from negatively affecting the rheology of the formulation.
• Dissolution Order: It is generally recommended to dissolve PVP VA64 first, followed by the addition of PVP K90. Due to the larger molecular weight of PVP K90, it dissolves more slowly and may require higher temperatures and stirring speeds.
